Instead of flying only to the big airports where 10+ other airlines are flying, the most profitable routes are the ones flown to medium/small airports that you're competition isn't flying to (or maybe just a couple others are). My load factor is always dropping on the same exact routes, and my other, usually more profitable ones (one would think of them to be less profitable), hold their 100% LF indefinitely, or at least for a very long time. Therefore, leaving my account untouched for a week will only drop my overall LF to ~90%. And when it comes time to edit routes, there's not too many to do.
I know this is really mostly helpful in regions like the Middle East that aren't so oversaturated, but maybe everyone can try flying to that 20,000 passenger airport and see what happens. I fly from Dubai International Airport to this remote 100,000 passenger airport and it makes me 75,000 while my flight to much bigger Doha makes me only 25,000. :wink: